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Since the components are unrelated, the entities that are associated with the symbol can no longer find that entity. It is now gone. Therfor there is no way to detect a new reference to which you what it to be associated.
'Sup Dale! Exactly. Believe me, when I just recently replaced about 400 parts in a large assy that had changed (one screw part number replaced with a different one), it would have been nice to have some logic that asked me if this surface was to be replaced with that one, etc. I DID find a trick to significantly speed things up, but it still s#cked.
So, to the OP, No, sorry, there isn't.