Simplified reps in large assemblies can really help by allowing subsets of the models to pulled opened into session. Only one of the assembly simplified reps can be in session at once. If you are using different simplified reps on a single sheet this means that even moving your mouse across a drawing view can cause Creo to stop and reset the current simp rep in session to match that view then do it again as you move your mouse across another view. Currently I have users move the view they need to work on to a different sheet, do their work and move it back. This involves needing to change sheets several times slowing things down. Before that PTC's recommendation was to put each view on it's own sheet but that just isn't practical at times.
I would like to be able to set views to "Inactive for Selection" to avoid this issue. To work on a particular view you would Activate it and then you could deactivate it again when done. A small icon or other notification of the Inactive state could be shown when you move the cursor over an inactive view to alert someone who didn't create the drawing that this is the state of that view and perhaps one over in the drawing tree to show status. This would not be the same as having the view not update geometry changes, they would still happen. It just would prevent Creo from trying to select anything within that view when in the drawing.