When a computer wakes up from Sleep or Hibernation, Creo will automatically throw a "Unsaved data may have been lost" dialog. This will occur once per wake. i.e. if a computer gets bumped a number of times in the workplace, a user could return to hundreds of these dialog boxes. There is some critical limit where hitting "OK" doesn't seem to work anymore, and the user is resigned to just closing Creo altogether.
There should either be an internal limit of one of these dialog boxes (should not be just a simple interrupt style event), or an option to turn these off altogether.