In PTC Creo Simulation, it would be extremely advantageous to be able to specify run settings on a design study basis. By doing this one would be able to specify a unique previous mesh for a number of studies. Then one could run a batch file over the weekend for one model with multiple mesh configurations.
Also, one could specify the design study file location on a design study basis. This would allow a local directory to be specified for design studies currently being run and another location for archived results when local drives become full.