There may be a way if you know exactly how many mouse clicks are input. AutoIT has a function called _IsPressed that can check if a mouse button has been clicked. It can also check many other keys as well (CTRL, SHIFT, ALT, etc.).
Some words of caution with trying to automate the continuation of a mapkey based on mouse clicks:
If the user selects the wrong item(s), the mapkey will continue immediately after the click using the wrong input.
You need to make sure the mouse click was in the Creo Parametric window, and not the user clicking on some other program like Outlook.
The speed of the user "double clicking" may cause issues with capturing how many times the button was clicked.