RE: Desktop integration in Windchill 10.1 M040, Windows 7, Internet explorer 10 and in combination with
Sounds like RES Workspace is a thin client manager, deploying a common desktop environment to all users?
If so, your experience is correct. Windchill Desktop Integration does not support distributed thin clients or a multi-user environment like Windows Server or CITRIX. It is currently designed to be installed on a single machine, used by a single user and connected to a single Windchill server.
Distributed thin clients would require the execution of multiple WtWindows.exe processes all connected to unique users with a unique communication path to the Windchill server. PTC is actively investigating this type of environment, but I have no conclusive results to share at this time.