In Creo 2 - after placing the note (or other annotation), select the annotation filter at the bottom right of the screen,
Then select to highlight the annotation and right click to open the popup menu.
Next, select Text Style and adjust the font by unselecting the default check box and typing in the desired font size.
Click on OK and the font size (and any other change) is made.
Save the file to keep the change(s).
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