The Windchill Desktop Integration (DTI) does currently (WT 10.1M10) support the connection to serveral windchill servers.
But all these Windchill server must have the same Release and Datecode.
It is unlikely that all the different Windchill servers have the same datecode,
if often working with different Windchill Servers.
Therefore there must be a supported way to connect to different Windchill servers and datecodes from one client maschine.
The solution could be one of the three suggestions:
Support of upgrade compatibility (older versions of the DTI can work with later versions of Windchill Server)
Support of downgrade compatibility (latest version of the DTI can work with older Windchill Server)
Support of parallel installation of different buildcodes from the DTI on one client maschine to be able to use the correct DTI buildcode with a Windchill Server of the same buildcode. The user is able to choose, or even better DTI chosses, which buildcode is to be used with a Windchill Server.
I recommend that solution 3 should be the preffered solution.