Hi, I see no reason why you won't go for 64bits. Fist, it's definitely future. There is no drawbacks, all CPU's are already 64bits, OS cost is the same and RAM is cheap these days. We have all VMware machines on 64bits with 8GB of RAM and on such machine, you can run both 32bit and 64bit systems and you can also run two or more VM machines simultaneously. And finally, on 32bit OS like WinXP or Vista you can't use all 4 GB of RAM even if you have it installed. My 2 cents.