We want to run Windchill with IIS and Windows Integrated Authentication enabled.
Testing has not been performed with integrated authentication enabled to the best of my knowledge.
Theoretically everything should work fine if one enables this *and* basic authentication. Customers have done this -- and we address issues found in this configuration as best we can, irrespective of whether support for this is official.
Enabling *only* integrated (and not basic) authentication will cause some clients to break, though.