Global PLM Architecture reference

There is prospect we are working on for a global PLM project. There is a big group and multiple different companies acquired in years distributed to different locations. I would like to know if there is any customer references in which the master location has around more than 500 heavy users and another site where the latency is more than 250ms has also around 500 heavy users working with a replica? The prospect is willing to understand if this has been used before?