There are several ways to do this. If they are linearly situated, you only need on direction; you can use Pattern>Dimension if one of the hole's positioning dimensions is in the direction you desire; or you can use Pattern>Direction and select a side or plane to denote the direction; or you could even use a sketch with datum points to map the holes to the locations desired (best for non-regular pattering).
Direction and dimension patterns can be distributed in X-Y matrices as well, this is the second direction in the dialog. In fact, deeper in the dialog, you will be able to create diagonal vectors as well.
If this is not clear enough, please feel free to post more information about your request.
