run Creo Ansys Simulation on your computer you must instal the latest 6.0.x version of the following

[ptc-2140310]

I am using Creo Parametric Release 3.0 and DatecodeM140

CREO3.0挂Creo Advanced simulation Extension的模块 使用，

To run Creo Ansys Simulation on your computer you must instal the latest 6.0.x version of the following x64 .NET packages
Microsoft .NETCore.App
Microsoft .NET Desktop Runtime
Microsoft .AspNetCore.App
Download and install these packages, Start Creo again and then open Creo Ansys Simulation.

[VladimirN · Accepted solution]

• From "Help Center" - "Prerequisites for Running Creo Ansys Simulation": https://support.ptc.com/help/creo/creo_pma/r11.0/usascii/index.html#page/simulate/ansys_simulation/prerequisites_ansys_sim.html 
• Article - "Will updating to .NET 6.0 Runtime create any issues with running Ansys Simulation on Creo Parametric": https://www.ptc.com/en/support/article/CS414844