Use caution jumping above M080. I have recently found out that my HP with on-board grahics will not work above M080 without OpenGL disabled. If you are using an approved hardware configuration then you are fine. Just make sure before the jump up.
Windchill users, be aware that your Windchill cache is not supported if jumping more than one maintenance build code. We are in the process of moving from M030 to M090 and just found that out. Recommended practice is to upload or check in all new or modified objects from all workspaces prior to upgrade. Our internal MCAD AE discovered this when one of our users had some weird workspace behavior after upgrading.
David R. Martin II
Senior CAD Application Specialist