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IMPORTANT UPDATE:
I have been struggling through a file I created originally in Prime 9 that has 3 chart components. The first is a simple chart component with absolutely no modifications made to it, containing 24 curves. The second chart has 6 curves with customized legend, line styles, title, etc. The 3rd chart has 10 curves and all elements of the chart are customized heavily (chart title, legend, trace names, line type/color/thickness, axes names and tick mark font sizing on all elements, etc.). This 3rd chart continues to become corrupt after saving it - of course this is the one that needs to be published!
NOTE - Prime 10 seems to be "behaving" so far - hopefully this has been addressed in this latest version. Stay on the lookout for this issue with your chart components using Prime 9!