Creo ISDX does support 3D "sketching". This is an optional add on license but even if you do not have this license, you can still create 3D curves by using 2D sketches. Without ISDX you can use the following method to get your cavity surfaces of the part in the image.
If you are looking to use two orthographic projections (2D planar curves) to create curves in space, Creo does support this.
1) Capture the front, top and a side view from the reference model
2) Use trace sketch functionality to drop the views on two orthogonal planes in Creo to use as a visual guide to build your curves which will be used to create the surfaces needed to define the form.
Plan to exploit symmetry when surface modeling in Creo, your part appears to have planar symmetry, so you only need to model half of the form and then mirror it.
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