Anyone running a good Virtual Desktop setup?

I am looking into the virtual desktop world and have done a couple of POC's (Proof of Concepts) with vendors but have not come up with something that looks as smooth as our 'regular' desktops. I know I have seen it work, and have talked to people (not vendors but actual companies running this way) at the conference that say they are running this way and would never go back to 'regular' desktops, so I (and the vendors) know we must be missing something because there are happy people working this way today. I assume for sure we need the Nvidia Grid M6 cards, and we are testing using these already. So, I am looking for any details on the hardware companies are running with multiple Creo users. We also have a few heavy Ansys users but this uses ram more than video (although this will most likely affect Creo if they are running an analysis while we are trying to spin/pan/zoom/etc. models) so I feel I can throw ram at a system all day and not too worried about this one. But, for Creo, Adobe Cloud, SolidWorks Composer, and a few other small graphics programs, I will need a setup that will perform, at minimum, the same as our current 'regular' desktops. But I am obviously looking for even better performance in the end. Any current working setups out there that are willing to share would be appreciated.

Thanks,

Shane V.