Solved
Run directory?
This is PTC description for this config option.
Set the config.pro option load_ui_customization_run_dir to yes, in order to load creo_parametric_customization.ui from (and save changes to) the run directory
What is Run directory? In all my years of admin that term is unfamiliair. They have preached loadpoint directory, start-in folder, and working directory.

