Hi @Shanmu ,
Before i go into the detail or make any guess i would suggest you to mainly check couple of things:-
1./ Ensure your Environment variable is set mainly %PATH% &%MKS_IC_INSTANCE_DIR%
2./ Make sure you have read and write access to directory where %MKS_IC_INSTANCE_DIR% is pointed to otherwise choose an directory where you have an access.
3./ Close the Integrity client if running, please also check from Task Manager to be sure that it's not even running in background. Then backup and delete the following files/folders from %HOME%: .mks, IntegrityClient.rc, ICServicePack (Note: Client preferences, viewsets and sandboxes will be temporarily gone with this test if you have any) and restart the client.
And this is very good article to follow as already suggested :-
Article - CS123559 - Integrity Lifecycle Manager Client will not start on Windows (ptc.com)
Does this help?
Vielen Dank / Many Thanks,
Kapil Jain