I experienced same problem trying to install ThingWorks Studio 8.2.0 (8.2.0.8274) .
Looking at log file first error is when there is switch from C:\ drive to U:\ drive. Why?? U:\ drive is corporate network drive and I am installing with Admin rights.
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[02/23/2018 08:54:49] info: [twx-studio:initializer] Node version: 8.9.3
[02/23/2018 08:54:49] info: [twx-studio:initializer] ThingWorxStudio launched with the following arguments: _=[C:\Users\mf42cl\Documents], help=false, version=false, $0=..\..\..\..\..\..\Roaming\ThingworxStudio\studio-download.vuforia.io\dist\server\index.js
[02/23/2018 08:54:49] info: [twx-studio:initializer] ThingWorxStudio dir: U:\Documents\ThingWorxStudio , home dir: U:\Documents
[02/23/2018 08:54:49] error: [twx-studio:fileUtils] Node module link already created.
[02/23/2018 08:54:50] ar-extension version 8.2.0 (1.22.941)
[02/23/2018 08:54:52] info: [twx-studio:index] Studio Ready: listening on 127.0.0.1:3000
[02/23/2018 08:54:52] Status Message: Version 8.2.0 (8.2.0.2742)
[02/23/2018 08:54:52] error: [twx-studio:importProject] failed to import project StudioSample3DImport Error: EISDIR: illegal operation on a directory, readlink 'U:\Documents\ThingWorxStudio\Projects\StudioSample3DImport'
[02/23/2018 08:54:52] error: [twx-studio:importProject] failed to import project StudioSampleSpatial Error: EISDIR: illegal operation on a directory, readlink 'U:\Documents\ThingWorxStudio\Projects\StudioSampleSpatial'
[02/23/2018 08:54:52] error: [twx-studio:importProject] failed to import project StudioSampleEyewear Error: EISDIR: illegal operation on a directory, readlink 'U:\Documents\ThingWorxStudio\Projects\StudioSampleEyewear'
[02/23/2018 08:54:52] error: [twx-studio:importProject] failed to import project StudioSampleQuadcopter Error: EISDIR: illegal operation on a directory, readlink 'U:\Documents\ThingWorxStudio\Projects\StudioSampleQuadcopter'
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