I don't think there is an increase in chance of failure.
Paccar told me:
"We use relative accuracy. Our division that designs engines (castings) uses Absolute accuracy by default in their start parts…all other divisions that bring in their designs complain about performance"
There are other folks that say they haven't had issues. More reference:
https://community.ptc.com/t5/Part-Modeling/Relative-vs-Absolute-accuracy/td-p/190209
Also I don't know what version you are using but be aware that PTC made some changes in Creo 4 to how accuracies are handled. I had issues with an early build of Creo 4 that I (maybe incorrectly) pinned on the accuracy changes they made.