1. Try this tip - "Creo Agent did not initialize correctly. Please contact technical support if the issue persists": https://community.ptc.com/t5/PTC-Education-Forum/Creo-Agent-did-not-initialize-correctly-Please-cont...
2. A similar issue: https://community.ptc.com/t5/System-Administration/Creo-4-0-mistake-0x06000012/m-p/484701